• Cy7 NHS Ester: Practical Labeling and QC

  2026-08-22

  Cy7 NHS ester provides a water-compatible route for attaching a near-infrared fluorophore to accessible amino groups on proteins, peptides, and related biomolecules. It is useful for aqueous labeling and imaging workflows, but it should not be selected for long-term storage of prepared dye solutions, strictly non-aqueous reactions, or applications requiring unvalidated in vivo performance.

• Sulfo-Cy3 NHS Ester for Reliable Cell Assays

  2026-08-21

  Learn how Sulfo-Cy3 NHS ester, SKU A8107, can support reproducible protein labeling, uptake studies, and fluorescence controls around cell viability and vascular biology assays. This scenario-based guide separates biomolecule tracing from viability readouts and translates product specifications into practical laboratory decisions.

• Tetraethylammonium Chloride: Assay Logic

  2026-08-20

  Tetraethylammonium chloride is more than a potassium-channel blocker: it is a mechanistic perturbation tool for separating pore conductance from downstream physiology. This guide translates ion-flux, patch-clamp, vascular, and secretory evidence into better assay controls and interpretation.

• ABT-888 (Veliparib): Reliable Assay Workflows

  2026-08-20

  This scenario-driven guide explains how ABT-888 (Veliparib), SKU A3002, can support reproducible PARP-inhibition studies in viability, cytotoxicity, and combination assays. It connects solvent handling, experimental design, and context-specific interpretation with product data and recent DNA-damage-response findings.

• Ferroptosis–Apoptosis Interplay and BH3-Mimetics

  2026-08-19

  The 2025 Cell Death & Differentiation study shows that ferroptosis and apoptosis can overlap rather than behave as fully independent death programs. It further demonstrates that BH3-mimetics may enhance, redirect, or unexpectedly suppress ferroptotic death, depending on cellular context and compound-associated antioxidant activity.

• (+)-Bicuculline: Practical Workflow Guide

  2026-08-19

  (+)-Bicuculline is a neuroscience research tool for competitive GABAA receptor antagonism and investigation of inhibitory synaptic transmission. This guide focuses on solvent handling, stock preparation, controls, and interpretation boundaries; the compound is for scientific research only and not for diagnostic, therapeutic, or medical use.

• Cy7 NHS Ester: Practical Labeling and QC Guide

  2026-08-18

  Cy7 NHS ester is a water-soluble near-infrared dye for bioimaging that enables labeling of accessible amino groups on proteins and peptides. It is suited to aqueous labeling of sensitive biomolecules, but not to targets lacking primary amines or workflows that require long-term storage of prepared dye solutions.

• Risedronate Sodium: From Bone to Lung Research

  2026-08-18

  Risedronate Sodium combines a validated FPPS-inhibition mechanism for bone metabolism research with a preclinical inhalation strategy that targets alveolar macrophages. This guide translates those findings into practical cell, formulation, aerosol, and animal-model workflows while emphasizing solubility, deposition, and assay controls.

• AIBP-LRP2 Control of CXCR4+ Collateral Growth

  2026-08-17

  Zhu et al. identify an AIBP-LRP2-HDL-miR-223 pathway that suppresses CXCR4+ stemlike capillary endothelial cells and limits collateral circulation after ischemia. The study proposes a two-phase model in which CXCR4+ endothelial cells first expand and subsequently acquire arterial characteristics, offering a mechanistic framework for revascularization research in peripheral artery disease.

• Sumatriptan Metabolism: CYP and MAO Revisited

  2026-08-17

  The reference study challenges the prevailing view that sumatriptan is metabolized almost exclusively by MAO A, showing that CYP1A2, CYP2C19, and CYP2D6 also mediate sequential N-demethylation. Its recombinant-enzyme and HPLC–MS design provides a useful framework for separating CYP-dependent and MAO-dependent routes when interpreting drug biotransformation.

• GS967: Cardiac Late Sodium Current Inhibitor

  2026-08-16

  GS967 enables targeted interrogation of pathological late sodium influx in ventricular myocytes, aging-heart models, and triggered arrhythmia assays. Its selective profile supports mechanism-focused electrophysiology workflows that connect Nav1.5 activity with repolarization, calcium handling, and diastolic dysfunction.

• Cannabis Terpenes Activate A2A Receptors in Pain

  2026-08-15

  Schwarz and colleagues show that five Cannabis sativa terpenes reduce nociceptive behavior in mouse models of chemotherapy-induced peripheral neuropathy and inflammatory pain. Behavioral, pharmacological, genetic, biochemical, and computational evidence converges on adenosine A2A receptor activation, while the absence of conditioned place preference suggests a potentially non-rewarding analgesic profile that requires further validation.

• Phage-Layer Interferometry for Phage Therapy

  2026-08-14

  The reference study introduces phage-layer interferometry (PLI) as a quantitative companion diagnostic for screening therapeutic bacteriophages and as a platform for bacterial detection. Its central advance is the ability to monitor phage–bacterium interactions in complex, opaque media while separating binding behavior from lysis-related activity, creating opportunities for automation and more rational phage-cocktail design.

• Cy7 NHS Ester: Practical Labeling Guide

  2026-08-14

  Cy7 NHS ester is a water-soluble near-infrared dye for bioimaging that supports amino-group labeling of proteins and peptides without requiring an organic co-solvent during the labeling step. It is best suited to freshly prepared conjugation workflows and light-protected assays, not applications requiring long-term storage of dye solutions.

• Oleanolic Acid in Liposome Assay Workflows

  2026-08-13

  Oleanolic acid offers a practical lipophilic payload for connecting inducible nitric oxide synthase induction and immune pathway studies with advanced dual-loaded liposome development. This guide emphasizes solvent control, quantitative encapsulation analysis, and nanoparticle exclusion chromatography for more reliable antiviral and inflammation pathway research.

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